杨波,1986.09-,中国科学技术大学细胞生物学博士学位。2014年入选leyu·乐鱼(中国)体育官方网站“太行青年学者”。目前研究方向为分子免疫学,主要从事宿主抗病毒免疫机制研究。主持国家自然科学基金2项;以第一作者或通讯作者在Cellular & Molecular Immunology、J Immunol、FEBS Letter、Scientific Reports等杂志上发表论文7篇。 学术任职: 中国免疫学会会员 发表SCI论文一览表(#为第一作者,*为通讯作者) Yang B#, Song D, Liu Y, Cui Y, Lu G, Di W, Xing H, Ma L, Guo Z, Guan Y, Wang H, Wang J. IFI16 regulates HTLV-1 replication through promoting HTLV-1 RTI-induced innate immune responses. FEBS Lett. 2018 May; 592(10):1693-1704. doi: 10.1002/1873-3468.13077. IF=2.99 Wang J, Song D, Liu Y, Lu G, Yang S, Liu L, Gao Z, Ma L, Guo Z, Zhang C,Wang H, Yang B*. HLA-DMB restricts human T-cell leukemia virus type-1 (HTLV-1) protein expression via regulation of ATG7 acetylation. Sci Rep. 2017 Oct 31;7(1):14416. doi: 10.1038/s41598-017-14882-z. IF=4.8 Jie Wang, Lixia Kang, Lu Liu, Shuai Yang, Di Song, Lingling Ma, Zhixiang Guo, Huaxia Ding, Hui Wang and Bo Yang*. Ku70 senses the HTLV-1 DNA and modulates HTLV-1 replication. The Journal of immunology. 2017 Oct 1; 199(7):2475-2482. doi: 10.4049/jimmunol.1700111. IF=4.8 Jie Wang, Shuai Yang, Lu Liu, Hui Wang and Bo Yang*. HTLV-1 Tax impairs K63-linked ubiquitination of STING to evade host innate immunity. Virus research. 2017 Mar 15;232:13-21. doi: 10.1016/j.virusres.2017.01.016. IF=2.7 Bo Yang#, Jie Wang and Bing Sun. Trim21: a novel negative regulator in DNA sensor signaling. Cell Mol Immunol. 2013 May; 10(3):190-2. doi: 10.1038/cmi.2013.12. IF=8.2 Jie Wang, Bo Yang#, Yu Hu, Yuhan Zheng, Leilei Yang, Meilin Qin and Bing Sun. Negative regulation of Nmi on virus-triggered type I IFN production by targeting IRF7. The Journal of immunology. 2013 Sep 15; 191(6):3393-9. doi: 10.4049/jimmunol. IF=4.8 Bo Yang#, Jie Wang, Yanming Wang, Haiyan Zhou, Xiaodong Wu, Zhigang Tian, and Bing Sun. Novel function of Trim44 promotes an antiviral response by stabilizing VISA. The Journal of immunology. 2013 Apr 1;190(7):3613-9. doi: 10.4049/jimmunol. IF=4.8
主持的重大科研项目: Trim7通过影响ATG7的泛素化修饰调控自噬的功能与机制研究,杨波,国家自然科学基金 2018.01-2020.12,No. U1704183,50万元; MHCⅡ类分子HLA-DM在HTLV-1复制过程中的功能和机制研究,杨波,国家自然科学基金 2015.01-2017.12,No. 31400776,25万元;
近五年来获批专利: S100A10 mRNA在α-干扰素诱导抑郁症中的作用(201510165415.9),专利权人:王辉、郭继强、张文、杨波、王洁、丁华夏、李桂芬
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