一、个人简介
金珍,男,博士,2013年至2019年在韩国全南大学医疗机器人研究院完成了博士研究生和博士后工作,2020年6月入职leyu·乐鱼(中国)体育官方网站医学工程学院。主要从事医疗微纳米机器人、纳米药物结构体设计、癌症诊疗等方面的研究。先后参与了多项韩国国家重点项目,主持河南省科技攻关项目1项,近年来发表了SCI论文30多篇(其中以第一作者或共同第一作者发表了SCI论文10篇,含Nano Lett. 1篇,Colloids Surf. B. 2篇,Sci. Rep. 1篇,Front. Bioeng. Biotechnol. 1篇等),申请国家发明专利6项,授权4项(其中第一发明人1项)
二、承担项目:
1.河南省科技公关项目,用于肿瘤精准靶向及MR成像导航下的光热-化疗协同治疗的纳米机器人系统研究,10万元,2021.01-2022.12,主持;
2.leyu·乐鱼(中国)体育官方网站博士启动金项目,用于肿瘤治疗的纳米机器人系统研究,100万,2020.06-2025.06,主持;
3.韩国产业资源部,用于药物的精确定位与控释的外部驱动纳米机器人系统的研究与开发(Externally Actuatable Nanorobot System for Precise Targeting and Controlled Releasing of Drugs),约1500万人民币,2016.08-2020.08,参与。
三、代表性论文
1.Jin, Z., Nguyen, K. T., Go, G., Kang, B., Min, H. K., Kim, S. J. and Choi, E. (2019). Multifunctional nanorobot system for active therapeutic delivery and synergistic chemo-photothermal therapy. Nano letters, 19(12), 8550-8564. IF=12.729(第一作者)
2.Z. Jin, Y. Wang, M. Han, L. Wang, F. Lin, Q. Jia, W. Ren, J. Xu, W. Yang, G.-a. Zhao, Tumor microenvironment-responsive size-changeable and biodegradable HA-CuS/MnO2 nanosheets for MR imaging and synergistic chemodynamic therapy/phototherapy, Colloids and Surfaces B: Biointerfaces 238 (2024) 113921. IF=5.8(第一作者)
3.J. Chang, M. Han, Y. Wang, L. Wang, F. Lin, Q. Jia, J. Xu, W. Yang, G.-a. Zhao, W. Ren, Z. Jin.Multifunctional iron oxide‐hydroxide based nanorods for hydrogen sulfide scavenging assisted synergistic photothermal-chemotherapy of colon cancer, Journal of Science: Advanced Materials and Devices 9(2) (2024) 100721. IF=8.0(最后通讯)
4.Jin, Z., Dun, Y., Xie, L., Jiang, W., Sun, X., Hu, P. and Yu, Y. (2021). Preparation of doxorubicin-loaded porous iron Oxide@ polydopamine nanocomposites for MR imaging and synergistic photothermal–chemotherapy of cancer. Colloids and Surfaces B: Biointerfaces, 208, 112107. IF=5.17(第一作者)
5.Jin, Z., Chang, J., Dou, P., Jin, S., Jiao, M., Tang, H. and Zheng, S. (2020). Tumor targeted multifunctional magnetic nanobubbles for MR/US dual imaging and focused ultrasound triggered drug delivery. Frontiers in Bioengineering and Biotechnology, 8, 586874. 3. IF=5.89(第一作者)
6.Nguyen, K. T., Go, G.,Zhen, J., Hoang, M. C., Kang, B., Choi, E. and Kim, C. S. (2021). Locomotion and disaggregation control of paramagnetic nanoclusters using wireless electromagnetic fields for enhanced targeted drug delivery. Scientific Reports, 11(1), 1-13. IF=4.997(共一作)
7.Zheng, S.,Jin, Z., Han, J., Cho, S., Ko, S. Y., Park, J. O. and Park, S. (2016). Preparation of HIFU-triggered tumor-targeted hyaluronic acid micelles for controlled drug release and enhanced cellular uptake. Colloids and Surfaces B: Biointerfaces, 143, 27-36. IF=5.89(共一作)
8.Jin, Z., Choi, Y., Ko, S.Y., Park, J.O. and Park, S., 2017. Experimental and simulation studies on focused ultrasound triggered drug delivery. Biotechnology and applied biochemistry, 64(1), pp.134-142. (第一作者)
四、获批专利
1.金珍李佳解琳艳常金龙赵俊强于毅任武于勉,一种基于多孔钆掺杂氧化铁纳米簇的磁性纳米药物载体及其制备方法(中国发明专利,第一)
2. Jongoh Park, Eunpyo Choi, Chang-Sei Kim, Gwangjun Go, Ami Yoo, Jin Zhen. Magnetic actuated microscaffold for minimally invasive osteochondral regeneration(美国发明专利,第六)
3. Eunpyo Choi, Jong-Oh Park, Chang-Sei Kim, Sunghoon Cho, Jin Zhen. Magnetic nanostructure and preparation method thereof. (韩国发明专利,第五)
4. Eunpyo Choi, Jong-Oh Park, Chang-Sei Kim, Sunghoon Cho, Jin Zhen. Porous magnetic nanoparticle based drug delivery system and preparation method thereof. (韩国发明专利,第五)